News & Insights
Research updates, scientific collaborations, industry events, and stories behind DR.HUI and HA35.
Advancing Beauty and Health through Bioactive Hyaluronan Science
Explore the latest research, collaborations, scientific events, and developments from DR.HUI and the HA35 research platform.
A Little-Known Amgen Story: The CAG Promoter and GC-Rich Gene Expression
Apr 08,2026
A personal scientific recollection of Dr. Hui's years in mammalian gene-expression research, tracing the development of chicken β-actin/CAG promoter technology and the origins of his later work on GC-rich DNA and recombinant protein expression.
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Dr. Hui and Team Visit Dr. Janet Denlinger, a Pioneer in Hyaluronan Research
Mar 11,2026
Dr. Hui and his research team visited Dr. Janet L. Denlinger, co-founder of Biomatrix and a long-time contributor to hyaluronan science, for an exchange on the history, development, and future of HA research.
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Mar 03,2026
Dr. Hui visited Professor Vera Gorbunova’s laboratory at the University of Rochester to discuss hyaluronic acid biology, naked mole-rat longevity, and new hypotheses surrounding the rapid biological effects of HA35.
DR.HUI Presents 12 HA35 Research Projects at ISHAS 2025
Feb 25,2026
DR.HUI presented 12 HA35 research projects at ISHAS 2025, spanning molecular characterization, sensory signaling, pain and itch, skin and oral applications, absorption, and in vivo distribution.
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Molecular Weight Shapes Red Blood Cell Interactions: New Study on Low-Molecular-Weight Hyaluronan
Mar 17,2026
Published in Frontiers in Physiology, the study reveals a clear molecular-weight-dependent interaction between low-molecular-weight hyaluronan and red blood cells and explores its potential use in functional quality control.
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How HA35 May Modulate Inflammation: Immune Signaling, Cell Migration, and Lymphatic Transport
Mar 17,2026
Recent studies suggest that HA35 may influence inflammation through multiple pathways, including inflammatory signaling, immune-cell migration, CD44-associated interactions, and lymphatic transport.
How HA35 Modulates Pain: New Evidence from TRPV1 and TRPA1
Mar 17,2026
A new electrophysiology study shows that HA35 inhibits both TRPV1 and TRPA1, providing mechanistic evidence for the rapid pain- and itch-related responses observed with low-molecular-weight hyaluronan.
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Mechanisms of 35 kDa Hyaluronan in Pain, Itch, and Tissue Inflammation
Jan 14,2026
Research on HA35 explores how rapid modulation of TRPV1/TRPA1 sensory signaling, immune-cell migration, and lymphatic transport may contribute to its observed effects on pain, itch, and local inflammation.
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