Bioactive Low-Molecular-Weight Hyaluronan: From Molecular Properties to Multiple Applications-Qingdao Huinuode Biotechnology Co., Ltd

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DR.HUI Empowering Beauty and Health with HA35 Biotechnology

Sep 04,2026

Bioactive Low-Molecular-Weight Hyaluronan: From Molecular Properties to Multiple Applications

HA35 is a defined low-molecular-weight hyaluronan platform centered around approximately 35 kDa. Research to date has explored its molecular characteristics, interactions with red blood cells and immune cells, TRPV1/TRPA1 sensory signaling, lymphatic transport, and a growing range of translational applications.

The following overview summarizes the development of HA35 from raw material and mechanistic research to functional products, patents, clinical observations, and presentations at the International Congress on Hyaluronic Acid Science (ISHAS).

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HA35 Clinical Studies and Scientific Publications: An Evidence Overview

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DR.HUI Empowering Beauty and Health with HA35 Biotechnology

Enable everyone to enjoy skincare and health solutions derived from genetic technology

Apr 08,2026

A Little-Known Amgen Story: The CAG Promoter and GC-Rich Gene Expression

A personal scientific recollection of Dr. Hui's years in mammalian gene-expression research, tracing the development of chicken β-actin/CAG promoter technology and the origins of his later work on GC-rich DNA and recombinant protein expression.

Mar 11,2026

Dr. Hui and Team Visit Dr. Janet Denlinger, a Pioneer in Hyaluronan Research

Dr. Hui and his research team visited Dr. Janet L. Denlinger, co-founder of Biomatrix and a long-time contributor to hyaluronan science, for an exchange on the history, development, and future of HA research.

Mar 03,2026

Dr. Hui Visits Professor Vera Gorbunova’s Laboratory to Explore Hyaluronic Acid Research in Naked Mole-Rats

Dr. Hui visited Professor Vera Gorbunova’s laboratory at the University of Rochester to discuss hyaluronic acid biology, naked mole-rat longevity, and new hypotheses surrounding the rapid biological effects of HA35.

Feb 25,2026

DR.HUI Presents 12 HA35 Research Projects at ISHAS 2025

DR.HUI presented 12 HA35 research projects at ISHAS 2025, spanning molecular characterization, sensory signaling, pain and itch, skin and oral applications, absorption, and in vivo distribution.

Mar 17,2026

Molecular Weight Shapes Red Blood Cell Interactions: New Study on Low-Molecular-Weight Hyaluronan

Published in Frontiers in Physiology, the study reveals a clear molecular-weight-dependent interaction between low-molecular-weight hyaluronan and red blood cells and explores its potential use in functional quality control.

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